This issue of Value in Health features an International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Good Research Practices Task Force Report that makes recommendations for statistical methods for mapping (sometimes referred to as “cross-walking” or “transfer to utility” [1]) to estimate health utility (HU) from non–preference-based outcome measures. The report states the consensus position of the ISPOR Task Force on Good Practices for Outcomes Research–Use of Mapping to Estimate Utility Values From Non–Preference-Based Outcome Measures for Cost per QALY Economic Analysis.