Like many authorities, health technology assessment (HTA) bodies are increasingly advocating for patient-centred decision-making. This talk will explore the role of patients’ perspectives and preferences in HTA by reviewing published guidance and case studies from the UK, Europe and Australia. We will explore how qualitative accounts are being incorporated into committee decisions and examine the growing, but still contained, role of quantitative patient preference data in technology appraisals. The talk will finish with a discussion of the logistical and methodological concerns that have been raised by researchers and the HTA bodies themselves.